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The mean renal clearance of zyvox is 40 ml min which suggests net tubular reabsorption.

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Information about Zyvox.

Diarrhoeanauseavomitinglocalised or general abdominal painconstipationdyspepsia.

*Clinical efficacy has been demonstrated for susceptible isolates in approved clinical indications.

Do not use this medicine if you have used an MAO inhibitor in the past 14 dayssuch as isocarboxazidlinezolidmethylene blue injectionphenelzinerasagilineselegilineor tranylcypromine.

The prevalence of acquired resistance may vary geographically and with time for selected species and local information on resistance is desirableparticularly when treating severe infectionsAs necessaryexpert advice should be sought when local prevalence of resistance is such that the utility of the agent in at least some types of infections is questionable.

Zyvox is indicated in adults for the treatment of community acquired pneumonia and nosocomial pneumonia when known or suspected to be caused by susceptible Gram positive bacteriaIn determining whether Zyvox is an appropriate treatmentthe results of microbiological tests or information on the prevalence of resistance to antibacterial agents among Gram positive bacteria should be taken into considerationsee section 5.1 for the appropriate organisms

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