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These are common and are often mildbut this can varyHot flushes and sweats may lessen after the first few monthsSome people continue to have them for as long as they take tamoxifen.

If you take tamoxifen for cancer that has spread to the bonesyou may get pain in your bones when you start taking itThis is sometimes called tumour flare.

Certain medicationsincluding diphenhydramineBenadrylcimetidineTagametand some antidepressants can also block the activity of the CYP2D6 enzymeThat’s why it’s very important to make sure your oncologist knows every medication you’re takingincluding supplementssays DrShah.

Tamoxifen or letrozole versus standard methods for women with breast cancer who freeze egg cells or embryos.

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